5 factors to consider in multi-gene targeting RNAi screens
Effective functional genomic screening depends on a variety of factors that need to be simultaneously addressed to obtain meaningful results. A recent Cell Reports paper demonstrates this by taking a holistic approach to siRNA screening with the use of multi-isoform/multi-gene targeting to address redundant paralogs and pathways in cancer cells.
Understanding Gene Networks with Combinatorial Gene Knockdown
Combinatorial gene knockdown with siPOOLs unveils complex gene networks, offering a deeper understanding of gene functions and interactions
