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Quick Order of raPOOL for CHRNA7

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Official Symbol:
CHRNA7
NCBI Gene ID:1139
Aliases: CHRNA7-2
NACHRA7
Official Full Name:cholinergic receptor nicotinic alpha 7 subunit
Species:human
Summary: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. The protein encoded by this gene forms a homo-oligomeric channel, displays marked permeability to calcium ions and is a major component of brain nicotinic receptors that are blocked by, and highly sensitive to, alpha-bungarotoxin. Once this receptor binds acetylcholine, it undergoes an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. This gene is located in a region identified as a major susceptibility locus for juvenile myoclonic epilepsy and a chromosomal location involved in the genetic transmission of schizophrenia. An evolutionarily recent partial duplication event in this region results in a hybrid containing sequence from this gene and a novel FAM7A gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].

 

Buy raPOOLs for CHRNA7

There is no existing raPOOL for your gene, hence a custom raPOOL set up service is required. Please add this to cart and proceed to choose the raPOOL scale required where 2, 5 or 10 nmol is sufficient for 20, 50 or 100 reactions with the recommended use of 100 pmol raPOOL per reaction.


Custom raPOOL Set Up Service   Click here for more information about Custom raPOOL Set Up Service
One-time raPOOL set up fee for a new gene.
Price: € 529,00

Includes design of new probes against target RNA. Charged on top of raPOOL 2, 5 or 10 price.

Charged once only, subsequent order of raPOOL follows raPOOL-2, 5 or 10 pricing.
 

raPOOL 10   Click here for more information about raPOOL 10
10nmol raPOOL
Price: € 1.155,00

Amount provided: 10 nmol. Sufficient for 100 reactions.

HPLC-purified, freeze-dried.
 

raPOOL 2   Click here for more information about raPOOL 2
2nmol raPOOL
Price: € 325,00

Amount provided: 2 nmol. Sufficient for 20 rxns.

HPLC-purified, freeze-dried.
 

raPOOL 5   Click here for more information about raPOOL 5
5 nmol raPOOL

Price: € 675,00

Amount provided: 5 nmol. Sufficient for 50 reactions.

HPLC-purified, freeze-dried.