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Quick Order of siPOOL for CYP3A4

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Please verify & confirm your selected Target Gene:

Official Symbol:
CYP3A4
NCBI Gene ID:1576
Content / Scale: CP33
CP34
CYP3A
CYP3A3
CYPIIIA3
CYPIIIA4
HLP
NF-25
P450C3
P450PCN1
VDDR3
Official Full Name:cytochrome P450 family 3 subfamily A member 4
Species:human
Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam, erythromycin, and chloroquine. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2020].

 

Buy a siPOOL (siRNA Pool) for CYP3A4

Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene CYP3A4.

Product Description:

siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.

Why 30 siRNAs?

Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.

Product Formats:

  • Individual siPOOLs: a pool of 30 distinct siRNAs provided as a single reagent
  • siPOOL kits: include an individual siPOOL and a standard negative control

As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.

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siPOOL- 2   Click here for more information about siPOOL- 2
2 nmol siPOOL
Price: € 295,00

2 nmol siPOOL
Pool of pre-selected ~30 siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL- 5   Click here for more information about siPOOL- 5
5 nmol siPOOL
Price: € 548,00

5 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL- 5 Kit   Click here for more information about siPOOL- 5 Kit
5 nmol siPOOL
5 nmol negative control siPOOL
Price: € 699,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 5 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-10   Click here for more information about siPOOL-10
10 nmol siPOOL
Price: € 692,00

10 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-10 Kit   Click here for more information about siPOOL-10 Kit
10 nmol siPOOL
10 nmol negative control siPOOL
Price: € 925,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 10 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-20   Click here for more information about siPOOL-20
20 nmol siPOOL
Price: € 1.041,00

20 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-20 kit   Click here for more information about siPOOL-20 kit
20 nmol siPOOL
20 nmol negative control siPOOL
Price: € 1.369,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 20 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-40   Click here for more information about siPOOL-40
40 nmol siPOOL
Price: € 1.665,00

40 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-40 kit   Click here for more information about siPOOL-40 kit
40 nmol siPOOL
40 nmol negative control siPOOL
Price: € 2.565,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 40 nmol / siPOOL.

HPLC-purified, in 50µM solution.