Not your Target Gener? Search again
| Official Symbol: | A2M |
| NCBI Gene ID: | 2 |
| Aliases: |
A2MD CPAMD5 FWP007 S863-7 |
| Official Full Name: | alpha-2-macroglobulin |
| Species: | human |
| Summary: | The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]. |
There is no existing raPOOL for your gene, hence a custom raPOOL set up service is required. Please add this to cart and proceed to choose the raPOOL scale required where 2, 5 or 10 nmol is sufficient for 20, 50 or 100 reactions with the recommended use of 100 pmol raPOOL per reaction.
|
Custom raPOOL Set Up Service
One-time raPOOL set up fee for a new gene. Price: € 529,00 |
|
|
Includes design of new probes against target RNA. Charged on top of raPOOL 2, 5 or 10 price. Charged once only, subsequent order of raPOOL follows raPOOL-2, 5 or 10 pricing. 
|
|
raPOOL 10
10nmol raPOOL Price: € 1.155,00 |
|
|
Amount provided: 10 nmol. Sufficient for 100 reactions. HPLC-purified, freeze-dried.
|
|
raPOOL 2
2nmol raPOOL Price: € 325,00 |
|
|
Amount provided: 2 nmol. Sufficient for 20 rxns. HPLC-purified, freeze-dried.
|
|
raPOOL 5
5 nmol raPOOL Price: € 675,00 |
|
|
Amount provided: 5 nmol. Sufficient for 50 reactions. HPLC-purified, freeze-dried.
|
