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Quick Order of siPOOL for MTOR

Not the Target Gene you're looking for? Search again

Please verify & confirm your selected Target Gene:

Official Symbol:
MTOR
NCBI Gene ID:2475
Content / Scale: FRAP
FRAP1
FRAP2
RAFT1
RAPT1
SKS
Official Full Name:mechanistic target of rapamycin kinase
Species:human
Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This kinase is a component of two distinct complexes, mTORC1, which controls protein synthesis, cell growth and proliferation, and mTORC2, which is a regulator of the actin cytoskeleton, and promotes cell survival and cell cycle progression. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Inhibitors of mTOR are used in organ transplants as immunosuppressants, and are being evaluated for their therapeutic potential in SARS-CoV-2 infections. Mutations in this gene are associated with Smith-Kingsmore syndrome and somatic focal cortical dysplasia type II. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Aug 2020].

 

Buy a siPOOL (siRNA Pool) for MTOR

Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene MTOR.

Product Description:

siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.

Why 30 siRNAs?

Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.

Product Formats:

  • Individual siPOOLs: a pool of 30 distinct siRNAs provided as a single reagent
  • siPOOL kits: include an individual siPOOL and a standard negative control

As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.

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siPOOL- 2   Click here for more information about siPOOL- 2
2 nmol siPOOL
Price: € 325,00

2 nmol siPOOL, only available when ordering 10 or more 2nmol siPOOLs.
Pool of pre-selected ~30 siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL- 5   Click here for more information about siPOOL- 5
5 nmol siPOOL
Price: € 548,00

5 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL- 5 Kit   Click here for more information about siPOOL- 5 Kit
5 nmol siPOOL
5 nmol negative control siPOOL
Price: € 699,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 5 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-10   Click here for more information about siPOOL-10
10 nmol siPOOL
Price: € 692,00

10 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-10 Kit   Click here for more information about siPOOL-10 Kit
10 nmol siPOOL
10 nmol negative control siPOOL
Price: € 925,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 10 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-20   Click here for more information about siPOOL-20
20 nmol siPOOL
Price: € 1.041,00

20 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-20 kit   Click here for more information about siPOOL-20 kit
20 nmol siPOOL
20 nmol negative control siPOOL
Price: € 1.369,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 20 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-40   Click here for more information about siPOOL-40
40 nmol siPOOL
Price: € 1.665,00

40 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-40 kit   Click here for more information about siPOOL-40 kit
40 nmol siPOOL
40 nmol negative control siPOOL
Price: € 2.565,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 40 nmol / siPOOL.

HPLC-purified, in 50µM solution.