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Quick Order of raPOOL for HSD11B2

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Official Symbol:
HSD11B2
NCBI Gene ID:3291
Aliases: AME
AME1
HSD11K
HSD2
SDR9C3
Official Full Name:hydroxysteroid 11-beta dehydrogenase 2
Species:human
Summary: There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension. [provided by RefSeq, Feb 2010].

 

Buy raPOOLs for HSD11B2

There is no existing raPOOL for your gene, hence a custom raPOOL set up service is required. Please add this to cart and proceed to choose the raPOOL scale required where 2, 5 or 10 nmol is sufficient for 20, 50 or 100 reactions with the recommended use of 100 pmol raPOOL per reaction.


Custom raPOOL Set Up Service   Click here for more information about Custom raPOOL Set Up Service
One-time raPOOL set up fee for a new gene.
Price: € 529,00

Includes design of new probes against target RNA. Charged on top of raPOOL 2, 5 or 10 price.

Charged once only, subsequent order of raPOOL follows raPOOL-2, 5 or 10 pricing.
 

raPOOL 10   Click here for more information about raPOOL 10
10nmol raPOOL
Price: € 1.155,00

Amount provided: 10 nmol. Sufficient for 100 reactions.

HPLC-purified, freeze-dried.
 

raPOOL 2   Click here for more information about raPOOL 2
2nmol raPOOL
Price: € 325,00

Amount provided: 2 nmol. Sufficient for 20 rxns.

HPLC-purified, freeze-dried.
 

raPOOL 5   Click here for more information about raPOOL 5
5 nmol raPOOL

Price: € 675,00

Amount provided: 5 nmol. Sufficient for 50 reactions.

HPLC-purified, freeze-dried.