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Quick Order of raPOOL for MDM4

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Official Symbol:
MDM4
NCBI Gene ID:4194
Aliases: BMFS6
HDMX
MDMX
MRP1
Official Full Name:MDM4 regulator of p53
Species:human
Summary: This gene encodes a nuclear protein that contains a p53 binding domain at the N-terminus and a RING finger domain at the C-terminus, and shows structural similarity to p53-binding protein MDM2. Both proteins bind the p53 tumor suppressor protein and inhibit its activity, and have been shown to be overexpressed in a variety of human cancers. However, unlike MDM2 which degrades p53, this protein inhibits p53 by binding its transcriptional activation domain. This protein also interacts with MDM2 protein via the RING finger domain, and inhibits the latter's degradation. So this protein can reverse MDM2-targeted degradation of p53, while maintaining suppression of p53 transactivation and apoptotic functions. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Feb 2011].

 

Buy raPOOLs for MDM4

There is no existing raPOOL for your gene, hence a custom raPOOL set up service is required. Please add this to cart and proceed to choose the raPOOL scale required where 2, 5 or 10 nmol is sufficient for 20, 50 or 100 reactions with the recommended use of 100 pmol raPOOL per reaction.


Custom raPOOL Set Up Service   Click here for more information about Custom raPOOL Set Up Service
One-time raPOOL set up fee for a new gene.
Price: € 529,00

Includes design of new probes against target RNA. Charged on top of raPOOL 2, 5 or 10 price.

Charged once only, subsequent order of raPOOL follows raPOOL-2, 5 or 10 pricing.
 

raPOOL 10   Click here for more information about raPOOL 10
10nmol raPOOL
Price: € 1.155,00

Amount provided: 10 nmol. Sufficient for 100 reactions.

HPLC-purified, freeze-dried.
 

raPOOL 2   Click here for more information about raPOOL 2
2nmol raPOOL
Price: € 325,00

Amount provided: 2 nmol. Sufficient for 20 rxns.

HPLC-purified, freeze-dried.
 

raPOOL 5   Click here for more information about raPOOL 5
5 nmol raPOOL

Price: € 675,00

Amount provided: 5 nmol. Sufficient for 50 reactions.

HPLC-purified, freeze-dried.