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|NCBI Gene ID:||5594|
|Official Full Name:||mitogen-activated protein kinase 1|
|Summary:|| This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014].|
There is no existing raPOOL for your gene, hence a custom raPOOL set up service is required. Please add this to cart and proceed to choose the raPOOL scale required where 2, 5 or 10 nmol is sufficient for 20, 50 or 100 reactions with the recommended use of 100 pmol raPOOL per reaction.
Custom raPOOL Set Up Service
One-time raPOOL set up fee for a new gene.
Price: € 529,00
Includes design of new probes against target RNA. Charged on top of raPOOL 2, 5 or 10 price.
Charged once only, subsequent order of raPOOL follows raPOOL-2, 5 or 10 pricing.
Price: € 1.155,00
Amount provided: 10 nmol. Sufficient for 100 reactions.
Price: € 325,00
Amount provided: 2 nmol. Sufficient for 20 rxns.
5 nmol raPOOL
Price: € 675,00
Amount provided: 5 nmol. Sufficient for 50 reactions.