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Official Symbol:	SMARCA4
NCBI Gene ID:	6597
Aliases:	BAF190 BAF190A BRG1 CSS4 MRD16 RTPS2 SNF2 SNF2-beta SNF2L4 SNF2LB SWI2 hSNF2b
Official Full Name:	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Species:	human
Summary:	The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].

 

Buy raPOOLs for SMARCA4

There is no existing raPOOL for your gene, hence a custom raPOOL set up service is required. Please add this to cart and proceed to choose the raPOOL scale required where 2, 5 or 10 nmol is sufficient for 20, 50 or 100 reactions with the recommended use of 100 pmol raPOOL per reaction.