Quick Order of siPOOL for SMARCA4

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Official Symbol:	SMARCA4
NCBI Gene ID:	6597
Content / Scale:	BAF190 BAF190A BRG1 CSS4 MRD16 RTPS2 SNF2 SNF2-beta SNF2L4 SNF2LB SWI2 hSNF2b
Official Full Name:	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Species:	human
Summary:	The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].

 

Buy a siPOOL (siRNA Pool) for SMARCA4

Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene SMARCA4.

Product Description:

siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.

Why 30 siRNAs?

Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.

Product Formats:

• Individual siPOOLs: a pool of 30 distinct siRNAs provided as a single reagent
• siPOOL kits: include an individual siPOOL and a standard negative control

As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.

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