Quick Order of siPOOL for BUB1B

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Please verify & confirm your selected Target Gene:

Official Symbol:	BUB1B
NCBI Gene ID:	701
Content / Scale:	BUB1beta BUBR1 Bub1A MAD3L MVA1 SSK1 hBUBR1
Official Full Name:	BUB1 mitotic checkpoint serine/threonine kinase B
Species:	human
Summary:	This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008].

 

Buy a siPOOL (siRNA Pool) for BUB1B

Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene BUB1B.

Product Description:

siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.

Why 30 siRNAs?

Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.

Product Formats:

• Individual siPOOLs: a pool of 30 distinct siRNAs provided as a single reagent
• siPOOL kits: include an individual siPOOL and a standard negative control

As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.

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