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|NCBI Gene ID:||7132|
|Official Full Name:||TNF receptor superfamily member 1A|
|Summary:|| This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016].|
There is no existing raPOOL for your gene, hence a custom raPOOL set up service is required. Please add this to cart and proceed to choose the raPOOL scale required where 2, 5 or 10 nmol is sufficient for 20, 50 or 100 reactions with the recommended use of 100 pmol raPOOL per reaction.
Custom raPOOL Set Up Service
One-time raPOOL set up fee for a new gene.
Price: € 529,00
Includes design of new probes against target RNA. Charged on top of raPOOL 2, 5 or 10 price.
Charged once only, subsequent order of raPOOL follows raPOOL-2, 5 or 10 pricing.
Price: € 1.155,00
Amount provided: 10 nmol. Sufficient for 100 reactions.
Price: € 325,00
Amount provided: 2 nmol. Sufficient for 20 rxns.
5 nmol raPOOL
Price: € 675,00
Amount provided: 5 nmol. Sufficient for 50 reactions.