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| Official Symbol: | CASR |
| NCBI Gene ID: | 846 |
| Content / Scale: |
CAR EIG8 FHH FIH GPRC2A HHC HHC1 HYPOC1 NSHPT PCAR1 hCasR |
| Official Full Name: | calcium sensing receptor |
| Species: | human |
| Summary: | The protein encoded by this gene is a plasma membrane G protein-coupled receptor that senses small changes in circulating calcium concentration. The encoded protein couples this information to intracellular signaling pathways that modify parathyroid hormone secretion or renal cation handling, and thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene are a cause of familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. [provided by RefSeq, Aug 2017]. |
Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene CASR.
siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.
Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.
As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.
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siPOOL- 2
2 nmol siPOOL Price: € 325,00 |
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2 nmol siPOOL, only available when ordering 10 or more 2nmol siPOOLs. Pool of pre-selected ~30 siRNAs against the target gene. HPLC-purified, in 50µM solution. 
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siPOOL- 5
5 nmol siPOOL Price: € 548,00 |
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5 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution.
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siPOOL- 5 Kit
5 nmol siPOOL 5 nmol negative control siPOOL Price: € 699,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 5 nmol / siPOOL. HPLC-purified, in 50µM solution.
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siPOOL-10
10 nmol siPOOL Price: € 692,00 |
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10 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution.
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siPOOL-10 Kit
10 nmol siPOOL 10 nmol negative control siPOOL Price: € 925,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 10 nmol / siPOOL. HPLC-purified, in 50µM solution.
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siPOOL-20
20 nmol siPOOL Price: € 1.041,00 |
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20 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution.
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siPOOL-20 kit
20 nmol siPOOL 20 nmol negative control siPOOL Price: € 1.369,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 20 nmol / siPOOL. HPLC-purified, in 50µM solution.
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siPOOL-40
40 nmol siPOOL Price: € 1.665,00 |
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40 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution.
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siPOOL-40 kit
40 nmol siPOOL 40 nmol negative control siPOOL Price: € 2.565,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 40 nmol / siPOOL. HPLC-purified, in 50µM solution.
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