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Quick Order of siPOOL for CBL

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Please verify & confirm your selected Target Gene:

Official Symbol:
CBL
NCBI Gene ID:867
Content / Scale: C-CBL
CBL2
FRA11B
NSLL
RNF55
Official Full Name:Cbl proto-oncogene
Species:human
Summary: This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder. [provided by RefSeq, Jul 2016].

 

Buy a siPOOL (siRNA Pool) for CBL

Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene CBL.

Product Description:

siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.

Why 30 siRNAs?

Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.

Product Formats:

  • Individual siPOOLs: a pool of 30 distinct siRNAs provided as a single reagent
  • siPOOL kits: include an individual siPOOL and a standard negative control

As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.

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siPOOL- 2   Click here for more information about siPOOL- 2
2 nmol siPOOL
Price: € 295,00

2 nmol siPOOL
Pool of pre-selected ~30 siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL- 5   Click here for more information about siPOOL- 5
5 nmol siPOOL
Price: € 548,00

5 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL- 5 Kit   Click here for more information about siPOOL- 5 Kit
5 nmol siPOOL
5 nmol negative control siPOOL
Price: € 699,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 5 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-10   Click here for more information about siPOOL-10
10 nmol siPOOL
Price: € 692,00

10 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-10 Kit   Click here for more information about siPOOL-10 Kit
10 nmol siPOOL
10 nmol negative control siPOOL
Price: € 925,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 10 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-20   Click here for more information about siPOOL-20
20 nmol siPOOL
Price: € 1.041,00

20 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-20 kit   Click here for more information about siPOOL-20 kit
20 nmol siPOOL
20 nmol negative control siPOOL
Price: € 1.369,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 20 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-40   Click here for more information about siPOOL-40
40 nmol siPOOL
Price: € 1.665,00

40 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-40 kit   Click here for more information about siPOOL-40 kit
40 nmol siPOOL
40 nmol negative control siPOOL
Price: € 2.565,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 40 nmol / siPOOL.

HPLC-purified, in 50µM solution.