Quick Order of siPOOL for CD44

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Please verify & confirm your selected Target Gene:

Official Symbol:	CD44
NCBI Gene ID:	960
Content / Scale:	CDW44 CSPG8 ECMR-III HCELL HUTCH-I IN LHR MC56 MDU2 MDU3 MIC4 Pgp1
Official Full Name:	CD44 molecule (Indian blood group)
Species:	human
Summary:	The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]. Sequence Note: This RefSeq record represents the CD44*001.1.1 allele.

 

Buy a siPOOL (siRNA Pool) for CD44

Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene CD44.

Product Description:

siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.

Why 30 siRNAs?

Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.

Product Formats:

• Individual siPOOLs: a pool of 30 distinct siRNAs provided as a single reagent
• siPOOL kits: include an individual siPOOL and a standard negative control

As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.

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