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Quick Order of siPOOL for CD59

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Please verify & confirm your selected Target Gene:

Official Symbol:
CD59
NCBI Gene ID:966
Content / Scale: 16.3A5
1F5
EJ16
EJ30
EL32
G344
HRF-20
HRF20
MAC-IP
MACIF
MEM43
MIC11
MIN1
MIN2
MIN3
MIRL
MSK21
p18-20
Official Full Name:CD59 molecule (CD59 blood group)
Species:human
Summary: This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].

 

Buy a siPOOL (siRNA Pool) for CD59

Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene CD59.

Product Description:

siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.

Why 30 siRNAs?

Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.

Product Formats:

  • Individual siPOOLs: a pool of 30 distinct siRNAs provided as a single reagent
  • siPOOL kits: include an individual siPOOL and a standard negative control

As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.

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siPOOL- 2   Click here for more information about siPOOL- 2
2 nmol siPOOL
Price: € 295,00

2 nmol siPOOL
Pool of pre-selected ~30 siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL- 5   Click here for more information about siPOOL- 5
5 nmol siPOOL
Price: € 548,00

5 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL- 5 Kit   Click here for more information about siPOOL- 5 Kit
5 nmol siPOOL
5 nmol negative control siPOOL
Price: € 699,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 5 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-10   Click here for more information about siPOOL-10
10 nmol siPOOL
Price: € 692,00

10 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-10 Kit   Click here for more information about siPOOL-10 Kit
10 nmol siPOOL
10 nmol negative control siPOOL
Price: € 925,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 10 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-20   Click here for more information about siPOOL-20
20 nmol siPOOL
Price: € 1.041,00

20 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-20 kit   Click here for more information about siPOOL-20 kit
20 nmol siPOOL
20 nmol negative control siPOOL
Price: € 1.369,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 20 nmol / siPOOL.

HPLC-purified, in 50µM solution.
 

siPOOL-40   Click here for more information about siPOOL-40
40 nmol siPOOL
Price: € 1.665,00

40 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene.

HPLC-purified, in 50µM solution.
 

siPOOL-40 kit   Click here for more information about siPOOL-40 kit
40 nmol siPOOL
40 nmol negative control siPOOL
Price: € 2.565,00

This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human.

Amount provided: 40 nmol / siPOOL.

HPLC-purified, in 50µM solution.