Human Cytoplasm riboPOOL

The Human Cytoplasm-only riboPOOL is designed to efficiently deplete cytoplasmatic ribosomal RNA (rRNA) from human RNA samples. It does not deplete mitochondrial rRNAs. The product is compatible with most downstream applications, including different next generation sequencing workflows (both short and long-read sequencing).


The Human Cytoplasm-Only riboPOOL covers the following sequences:

Sequence Type Covered
28S rRNA Cytosolic Yes
18S  rRNA Cytosolic Yes
5.8S  rRNA Cytosolic Yes
5S rRNA Cytosolic Yes
12S  rRNA Mitochondrial No
16S  rRNA Mitochondrial No


Remarkably, only about 1-2% of the human genome encodes for proteins. The remaining portion, once considered "junk DNA," contains regulatory elements and non-coding regions critical for gene regulation and function.



  • Enzyme-free, fast & easy workflow
  • Compatible with most downstream applications
  • Wide range of input RNA amounts
  • Possibility of combining with other riboPOOLs
  • Compatible with lab automated workflows


Available Formats

riboPOOLs kits with cleanUP module

riboPOOL Probes Only