Seed effects persist in hyperdimensional space
Delve into the challenge of off-target effects in seed-based RNAi. Carpenter lab's study reveals persistent seed effects even in expanded phenotypic hyperspace, emphasizing the need for precise gene-specific knockdown reagents
Knocking out the phenotype
Explore the implications of gene knockout on phenotype. Learn from recent research indicating a lack of phenotypic response when knocking out klf2a, contrasting with knockdown outcomes.