RNA Research Technotes
siTOOLs
siPOOL Stability During Shipping: Technical Guide
Discover comprehensive data on siPOOL stability and our optimized shipping protocols. This technical guide explains how we deliver siPOOLs quickly while maintaining RNA integrity through specialized handling and storage conditions during transit.
siRNA Off-target Effects - Causes, Extent & Impact
Learn about siRNA off-target effects. A reference-rich guide describing the mechanism by which siRNA off-targets are produced, the penetrance and extent of siRNA off-target effects, and the impact siRNA off-targets have on experimental research.
Ways to Reduce siRNA Off-target Effects
Understand current established techniques to reduce siRNA off-target effects, including the siPOOL approach. From siRNA concentration, chemical modification and siRNA design, this is a detailed technical overview of each approach and their pros and cons. We also provide a non-bias assessment of the effectiveness of each approach using data-driven bioinformatic analysis.
Efficient ribosomal RNA depletion across multiple species and input amounts in 70 min
By Bioanalyzer/rtq PCR assessment, we show riboPOOL-mediated rRNA depletion is efficient across a broad RNA input range (100 ng - 5 μg), when applied in combination and with a fast workflow time of 70 min.