Fast, semi-automated fractionation with the siFractor

The siFractor is a device for semi-automated fractionation of samples from gradient centrifugation tubes. 

Manual fractionation of samples contained in centrifugation tubes is laborious, and error-prone. Parameters such as light absorbance are typically monitored from the isolated fractions, thus limiting resolution. Hence, precise isolation of the molecules of interest from the centrifugation tube without contaminations is hampered. With the siFractor, you can overcome these limitations and much more.

Benefits of using the siFractor

  • Simple and reproducible
  • Precise & semi-automated
  • Fast & leak-free


Applications of the siFractor

  • Structural biology: Isolation of protein complexes and RNPs
  • Exosome research: Purification of extracellular vesicles
  • Translatome studies: Ribosome profiling (Ribo-Seq)


Customer testimonials

"Due to its robust construction, the siFractor is much easier to handle than the device that we previously used for gradient fractionation (ISCO system). The quality of the separation was also very good in our experiments. The big advantage is that you don't have to buy all the components, i.e. pump, UV lamp and fractionator, as with other fractionation systems, but can use all of these components from the Äkta. This not only saves a lot of money, but also space"

Dr. Brigitte Pertschy (Group Leader, Institute of Molecular Biosciences, University of Graz, Austria)