Comparing silencing for CDS and 3' UTR siRNAs
In some cases, it may be preferable to only target the 3′ UTR of an mRNA. For example, the CDS may be highly similar to a related paralog gene that should not be co-targeted.
In some cases, it may be preferable to only target the 3′ UTR of an mRNA. For example, the CDS may be highly similar to a related paralog gene that should not be co-targeted.