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Literature
Publications citing siPOOLs
A Double-Negative Prostate Cancer Subtype is Vulnerable to SWI/SNF-Targeting Degrader Molecules
2026 | Thienger | Cancer Research | Link
Nuclear speckles enable processing of RNA from GC-rich isochores
2026 | Małszycki | Cell | Link
Spectrin coordinates cell shape and signaling essential for epidermal differentiation
2026 | Soffer | Journal of Cell Biology | Link
A neuregulin-like ligand and EGF receptor underpin Echinococcus multilocularis development
2026 | Koike | Frontiers in Cellular and Infection Microbiology | Link
LBR and LAP2 mediate heterochromatin tethering to the nuclear periphery to preserve genome homeostasis
2026 | Lewis | Nature cell biology | Link
Functional siRNA Screen Links Ras/MAPK and Wnt Pathway to EV Secretion in HCT-116 Colorectal Cancer Cells
2026 | Pätzold | Diseases | Link
Conserved patterns of transcriptional dysregulation, heterogeneity, and cell states in clear cell kidney cancer
2025 | Lombardi | Cell Reports | Link
Alginate-Dialdehyde-Based Reporter Ink Enabling Online Detection of Matrix Metalloproteinase Activity of Encapsulated Cells
2025 | Gantert | ACS Biomaterials Science & Engineering | Link
Development and validation of a high-throughput screening pipeline of compound libraries to target EMT
2025 | Jonckheere | Cell Death & Differentiation | Link
Loss of primary cilia promotes EphA2-mediated endothelial-to-mesenchymal transition in the ovarian tumor microenvironment
2025 | Cho | Molecular Oncology | Link
The human proteome with direct physical access to DNA
2025 | Trendel | Cell | Link
AnkyloblepharonEctodermal DefectsCleft Lip/Palate Syndrome-Linked p63 Mutations Disrupt Keratinocyte Proliferation and Survival Through Oxidative Stress and Impaired Slc7a11 Expression
2025 | Di girolamo | International Journal of Molecular Sciences | Link
Nonstop mutations cause loss of renal tumor suppressor proteins VHL and BAP1 and affect multiple stages of protein translation
2025 | Pal | Science Advances | Link
A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson's disease cell model
2025 | Höllerhage | Translational Neurodegeneration | Link
Epigenetic regulation of HOXA2 expression affects tumor progression and predicts breast cancer patient survival
2025 | De palma | Cell Death & Differentiation | Link
Prognostic marker Musashi-2 modulates DNA damage response and radioresistance in diffuse large B-cell lymphoma
2025 | Habig | Frontiers in Cell and Developmental Biology | Link
Cell-type specific effects of the long non-coding RNA HIF1A-AS3 on HIF1A expression in kidney cells
2025 | Reichelt-wurm | Scientific Reports | Link
Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses
2025 | Ren | Cancer Cell
Lead induces cell-autonomous proliferation and metabolic reprogramming of hepatocytes
2025 | Serra | Cell Death and Diseases | Link
PROCA11 early activation fuels prostate cancer neuroendocrine traits by regulating cell survival and migration
2025 | Cipolla | iScience | Link
Inhibition of TGF-beta signaling protects from alpha-synuclein induced toxicity
2025 | Chua | Cell Death Discovery | Link
Bat Dicer antiviral role and subcellular localization differ upon alphavirus infection in two distinct species
2025 | Gaucherand | Plos Pathogens | Link
dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe
2024 | Rodrigues | Nature Communications | Link
Leveraging multi-omics data to infer regulators of mRNA 3 end processing in glioblastoma
2024 | Mironov | Frontiers in Biomolecular Sciences | Link
A feedback loop between plakophilin 4 and YAP signaling regulates keratinocyte differentiation
2024 | Muller | iScience | Link
Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons
2024 | Marvian | Molecular Neurodegeneration | Link
Differentiation and Growth-Arrest-Related lncRNA (DAGAR): Initial Characterization in Human Smooth Muscle and Fibroblast Cells
2024 | De la cruz-thea | International Journal of Cancer | Link
The Role of T-Cadherin (CDH13) in Treatment Options with Garcinol in Melanoma
2024 | Staebler | Cancers | Link
Cyclophilin D plays a critical role in the survival of senescent cells
2024 | Protasoni | EMBO | Link
Proteomic profiling reveals CEACAM6 function in driving gallbladder cancer aggressiveness through integrin receptor, PRKCD and AKT/ERK signaling
2024 | Sugiyanto | Cell Death and Diseases | Link
N-terminal domain of polypyrimidine-tract binding protein is a dynamic folding platform for adaptive RNA recognition
2024 | Damberger | Nucleic Acids Research | Link
Release of mitochondrial dsRNA into the cytosol is a key driver of the inflammatory phenotype of senescent cells
2024 | Lopez-polo | Nature Communications | Link
Exploring the neuroprotective potential of Nrf2-pathway activators against annonacin toxicity
2024 | Costa | Scientific Reports | Link
Splicing control by PHF5A is crucial for melanoma cell survival
2024 | Meissgeier | Cell Proliferation | Link
HSF1 is a prognostic determinant and therapeutic target in intrahepatic cholangiocarcinoma
2024 | Cigliano | J Exp Clin Cancer Res | Link
Cilia defects upon loss of WDR4 are linked to proteasomal hyperactivity and ubiquitin shortage
2024 | Burkhalter | Cell Death and Diseases | Link
Chromosome 8p engineering reveals increased metastatic potential targetable by patient-specific synthetic lethality in liver cancer
2024 | Huth | Science Advances | Link
BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution
2024 | Tsukada | Molecular Cell | Link
Ribosomal protein L24 mediates mammalian microRNA processing in an evolutionarily conserved manner
2024 | Tzur | Cellular and Molecular Life Sciences | Link
CSDE1 Intracellular Distribution as a Biomarker of Melanoma Prognosis
2024 | Indacochea | MDPI Cancers | Link
Evoked Weibel-Palade Body Exocytosis Modifies the Endothelial Cell Surface by Releasing a Substrate-Selective Phosphodiesterase
2024 | Naß | Advance Science | Link
PPARG activation promotes the proliferation of colorectal cancer cell lines and enhances the antiproliferative effect of 5-fluorouracil
2024 | Schöckel | BMC Cancer | Link
Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence
2024 | Kluge | Cell Death and Diseases | Link
lncRNA LINC00941 modulates MTA2/NuRD occupancy to suppress premature human epidermal differentiation
2024 | Morgenstern | Life Science Alliance | Link
NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma
2024 | Devitt | Cell Communication and Signaling | Link
Basis of gene-specific transcription regulation by the Integrator complex
2024 | Sabath | Molecular Cell | Link
Plakophilin 4 controls the spatio-temporal activity of RhoA at adherens junctions to promote cortical actin ring formation and tissue tension
2024 | Müller | Cellular and Molecular Life Sciences | Link
WNT enhancing signals in pancreatic cancer are transmitted by LGR6
2023 | Wang | Aging | Link
Dysregulated Stem Cell Markers Musashi-1 and Musashi-2 are Associated with Therapy Resistance in Inflammatory Breast Cancer
2023 | Haiduk | Archives of Medical Research | Link
The Long Noncoding RNA LINC00958 Is Induced in Psoriasis Epidermis and Modulates Epidermal Proliferation
2023 | Luo | Journal of Investigative Dermatology | Link
Dengue virus NS1 secretion is regulated via importin-subunit β1 controlling expression of the chaperone GRp78 and targeted by the clinical drug ivermectin
2023 | Denolly | mBio | Link
Prion protein conversion at two distinct cellular sites precedes fibrillisation
2023 | Ribes | Nature Communications | Link
Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells
2023 | Hoes | iScience | Link
Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis
2023 | Klemm | BMC Cancer | Link
The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways
2023 | Berkane | Nature Communications | Link
Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment
2023 | Pelos | International Journal of Cancer | Link
GTPase activating protein DLC1 spatio-temporally regulates Rho signaling
2023 | Heydasch | eLife | Link
Expression of Bone Morphogenetic Protein 14 in Liver Disease and Cancer
2023 | Sommer | MDPI Livers | Link
Polarity signaling balances epithelial contractility and mechanical resistance
2023 | Rübsam | Scientific Reports | Link
Cryptosporidium uses CSpV1 to activate host type I interferon and attenuate antiparasitic defenses
2023 | Deng | Nature Communications | Link
Cold Atmospheric Plasma Triggers Apoptosis via the Unfolded Protein Response in Melanoma Cells
2023 | Zimmermann | MDPI Cancers | Link
MIA/CD-RAP Regulates MMP13 and Is a Potential New Disease-Modifying Target for Osteoarthritis Therapy
2023 | Staebler | MDPI Cells | Link
BET Inhibition Enhances TNF-Mediated Antitumor Immunity
2022 | Wellinger | Cancer Immunology Research | Link
Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation
2022 | Orth | Cell Reports | Link
Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism
2022 | D | Nucleic Acids Research | Link
The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors
2022 | Bartl | Nature Communications | Link
The Interplay of NEAT1 and miR-339-5p Influences on Mesangial Gene Expression and Function in Various Diabetic-Associated Injury Models
2022 | Reichelt-wurm | MDPI non-coding RNA | Link
Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis
2022 | Mestre-farràs | Nucleic Acids Research | Link
Optogenetic actuator–ERK biosensor circuits identify MAPK network nodes that shape ERK dynamics
2022 | Dessauges | Molecular systems biology | Link
Knockdown of the stem cell marker Musashi-1 inhibits endometrial cancer growth and sensitizes cells to radiation
2022 | Falke | Stem Cell Research & Therapy | Link
DUSP4 protects BRAF- and NRAS-mutant melanoma from oncogene overdose through modulation of MITF
2022 | Gutierrez-prat | Life Science Alliance | Link
A JAM-A–tetraspanin–αvβ5 integrin complex regulates contact inhibition of locomotion
2022 | Kummer | Journal of Cell Biology | Link
Transcriptomic landscapes of SARS-CoV-2-infected and bystander lung cells reveal a selective upregulation of NF-κB-dependent coding and non-coding proviral transcripts
2022 | Szachnowski | bioRxiv | Link
Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation
2022 | Hauffe | Cell Death Discovery | Link
Noncanonical Function of AGO2 Augments T-cell Receptor Signaling in T-cell Prolymphocytic Leukemia
2022 | Braun | AACR Journals | Link
Angpt2/Tie2autostimulatory loopcontrols tumorigenesis
2022 | Karabid | EMBO Molecular Medicine | Link
5'isomiR-183-5p|+2 Elicits Tumor Suppressor Activity in a Negative Feedback Loop with E2F1
2022 | Li | Research Square | Link
JAM-A interacts with α3β1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cells
2022 | Thölmann | Cellular and Molecular Life Sciences | Link
Ago-RIP Sequencing Identifies New MicroRNA-449a-5p Target Genes Increasing Sorafenib Efficacy in Hepatocellular Carcinoma
2022 | Reinkens | Journal of Cancer | Link
Probing protein ubiquitination in live cells
2022 | Qin | bioRxiv | Link
USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
2022 | Hertel | Cell Reports | Link
High‐throughput morphometric and transcriptomic profiling uncovers composition of naïve and sensory‐deprived cortical cholinergic VIP/CHAT neurons
2022 | Yayon | EMBO | Link
Screening of the siGPCR library in combination with cisplatin against lung cancers
2022 | Kim | Scientific Reports | Link
SNAP23-Mediated Perturbation of Cholesterol-Enriched Membrane Microdomain Promotes Extracellular Vesicle Production in Src-Activated Cancer Cells
2022 | Mitani | Biological and Pharmaceutical Bulletin | Link
Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors
2022 | Blümel | Cell Death and Diseases | Link
The lysosomal proteome of senescent cells contributes to the senescence secretome
2022 | Rovira | Aging Cell | Link
Targeting the Retinoblastoma/E2F repressive complex by CDK4/6 inhibitors amplifies oncolytic potency of an oncolytic adenovirus
2022 | Koch | Nature Communications | Link
Global and precise identification of functionalmiRNA targets in mESCs by integrative analysis
2022 | Schaefer | EMBO reports | Link
Systematic analysis of migration factors by MigExpress identifies essential cell migration control genes in non-small cell lung cancer
2021 | Pal | Molecular Oncology | Link
Comprehensive miRNome-Wide Profiling in a Neuronal Cell Model of Synucleinopathy Implies Involvement of Cell Cycle Genes
2021 | Findeiss | Frontiers in Cell and Developmental Biology | Link
Sequence- and structure-specific cytosine-5 mRNA methylation by NSUN6
2021 | Selmi | Nucleic Acids Research | Link
Deep neural networks identify signaling mechanisms of ErbB-family drug resistance from a continuous cell morphology space
2021 | Longden | Cell Reports | Link
Amphiregulin Regulates Melanocytic Senescence
2021 | Pommer | Cells | Link
DDX3 depletion represses translation of mRNAs with complex 5' UTRs
2021 | Calviello | Nucleic Acids Research | Link
YB-1 Oncoprotein Controls PI3K/Akt Pathway by Reducing Pten Protein Level
2021 | Delicato | MDPI genes | Link
Hepsin regulates TGFbsignaling via fibronectinproteolysis
2021 | Belitskin | EMBO reports | Link
AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation
2021 | Ghodke | Cell Press | Link
Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11
2021 | Gaza | Neoplasia | Link
Cold-inducible RNA binding protein promotes breast cancer cell malignancy by regulating Cystatin C levels
2021 | Ibdacochea | RNA | Link
Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation
2020 | Mercier | Nature cell biology | Link
Prevention of dsRNA-induced interferon signalingby AGO1x is linked to breast cancer cellproliferation
2020 | Ghosh | EMBO | Link
The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer
2020 | Gandhi | Nature Communications | Link
MICOS assembly controls mitochondrial innermembrane remodeling and crista junctionredistribution to mediate cristae formation
2020 | Stephan | EMBO | Link
HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth
2020 | Liebig | MDPI Cancers | Link
The UPR sensor IRE1a and the adenovirus E3-19K glycoprotein sustain persistent and lytic infections
2020 | Prasad | Nature Communications | Link
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
2020 | Marchetto | Nature Communications | Link
ALIX- and ESCRT-IIIdependent sorting of tetraspanins to exosomes
2020 | Larios | Journal of Cell Biology | Link
Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro
2019 | Mahli | MDPI Cells | Link
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy
2019 | Renner | Cell Reports | Link
MRTF-A controls myofbroblastic diferentiation of human multipotent stromal cells and their tumour-supporting function in xenograft models
2019 | Werner | Nature Scientific reports | Link
C-Jun drives melanoma progression in PTEN wild type melanoma cells
2019 | Kappelmann-fenzl | Cell Death and Diseases | Link
NEAT1 is overexpressed in Parkinsons diseasesubstantia nigra and confers drug-inducibleneuroprotection from oxidative stress
2019 | Simchovitz | The FASEB Journal | Link
The Delta Subunit of Rod-Specific Photoreceptor cGMP Phosphodiesterase (PDE6D) Contributes to Hepatocellular Carcinoma Progression
2019 | Dietrich | MDPI Cancers | Link
Role of MIA (melanoma inhibitory activity) in melanocyte senescence
2019 | Feuerer | Pigment Cell & Melanoma | Link
Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo Using Layer-by-Layer Nanoparticles
2019 | Choi | Advanced Funtional Materials | Link
53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage
2019 | Spies | Nature cell biology | Link
Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Is a Novel Prognostic Marker and Contributes to Sorafenib Resistance in Hepatocellular Carcinoma
2019 | Dietrich | Neoplasia | Link
Inhibition of peptidyl-prolyl isomerase (PIN1) and BRAF signaling to target melanoma
2018 | Braun | American Journal of Translational Research | Link
The long non-coding RNA LINC00941andSPRR5are novel regulators of humanepidermal homeostasis
2018 | Ziegler | EMBO reports | Link
SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation
2018 | Vendramin | Nature Structural and Molecular Biology | Link
Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer
2018 | Coscia | Cell | Link
FKBP51 modulates steroid sensitivity and NFκBsignalling: A novel anti-inflammatory drug target
2018 | Kästle | European Journal of Immunology | Link
Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1
2018 | Weber | Nature Communications | Link
Transition of responsive mechanosensitive elements from focal adhesions to adherens junctions on epithelial differentiation
2018 | Noethel | MBoC | Link
Nrf2 protects stellate cells from Smad-dependent cell activation
2018 | Prestigiacomo | PLOS ONE | Link
Novel short isoforms of adenylyl cyclase as negative regulators of cAMP production
2018 | Vallin | BBA Molecular Cell Research | Link
14-3-3 proteins regulate desmosomal adhesion via plakophilins
2018 | Rietscher | The Company of Biologist | Link
Genome-Scale Signatures of Gene Interaction from Compound Screens Predict Clinical Efficacy of Targeted Cancer Therapies
2018 | Jiang | Cell Systems | Link
Cervical cancer is addicted to SIRT1 disarming the AIM2 antiviral defense
2018 | So | Oncogene | Link
The Long Noncoding RNA Cancer Susceptibility 9 and RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein L Form a Complex and Coregulate Genes Linked to AKT Signaling
2018 | Klingenberg | Hepatology | Link
The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation
2018 | Polycarpu-schwarz | Oncogene | Link
CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival
2018 | Zeiner | Acta Neuropathologica Communications | Link
Lithium chloride effectively kills the honey bee parasite Varroa destructor by a systemic mode of action
2018 | Ziegelmann | Scientific Reports | Link
Challenges of CRISPR/Cas9 applications for long non-coding RNA genes
2017 | Goyal | Nucleic Acids Research | Link
BMP6-induced modulation of the tumor micro-milieu
2017 | Stieglitz | Oncogene | Link
Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition
2017 | Dietrich | Oncogene | Link
Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux
2017 | Ilina | Oncotarget | Link
A cautionary tale of sense-antisense gene pairs: independent regulation despite inverse correlation of expression
2017 | Goyal | Nucleic Acids Research | Link
ERAP1 overexpression in HPV-induced malignancies: A possible novel immuneevasion mechanism
2017 | Steinbach | Oncoimmunology | Link
Enhanced Stem Cell Differentiation and Immunopurification of Genome Engineered Human Retinal Ganglion Cells
2017 | Sluch | Stem Cell Research & Therapy | Link
Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors
2017 | Armento | International Journal of Cancer | Link
The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells
2017 | Nötzold | Scientific Reports | Link
A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis
2017 | Treiber | Molecular Cell | Link
Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper KinaseDependent Injury Signaling in Neurons
2017 | Welsbie | Neuron | Link
The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance
2017 | Seiler | Nucleic Acids Research | Link
Host AMPK Is a Modulator of Plasmodium Liver Infection
2016 | Ruivo | Cell Reports | Link
Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells
2016 | Ott | Oncotarget | Link
Slug Is Increased in Vascular Remodeling and Induces a Smooth Muscle Cell Proliferative Phenotype
2016 | Coll-bonfill | PLOS ONE | Link
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity
2016 | Adriaens | Nature Medicine | Link
SOX5 is involved in balanced MITF regulation in human melanoma cells
2016 | Kordaß | BMC Medical Genomics | Link
Biochemical isolation of Argonaute protein complexes by Ago-APP Judith Hauptmanna , Daniel Sch
2015 | Hauptmann | PNAS | Link
The stellate vascular smooth muscle cell phenotype is induced by IL-1β via the secretion of PGE2 and subsequent cAMP-dependent protein kinase A activation
2015 | Blirando | BBA Molecular Cell Research | Link
JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis
2015 | Tuncay | Nature Communications | Link
Importin- facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels
2015 | Schraivogel | Nucleic Acids Research | Link
Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33
2014 | Schönemann | Genes Dev | Link
Chemical Induction of Unfolded Protein Response Enhances Cancer Cell Killing through Lytic Virus Infection
2014 | Prasad | Journal of Virology | Link
Advances in RNAi Tools and Technologies
2013 | Smith-vikos | Omics | Link