siPOOLs

Cyclophilin D plays a critical role in the survival of senescent cells

2024 | Protasoni | EMBO | Link

Proteomic profiling reveals CEACAM6 function in driving gallbladder cancer aggressiveness through integrin receptor, PRKCD and AKT/ERK signaling

2024 | Sugiyanto | Cell Death and Diseases | Link

N-terminal domain of polypyrimidine-tract binding protein is a dynamic folding platform for adaptive RNA recognition

2024 | Damberger | Nucleic Acids Research | Link

Release of mitochondrial dsRNA into the cytosol is a key driver of the inflammatory phenotype of senescent cells

2024 | Lopez-polo | Nature Communications | Link

Exploring the neuroprotective potential of Nrf2-pathway activators against annonacin toxicity

2024 | Costa | Scientific Reports | Link

Splicing control by PHF5A is crucial for melanoma cell survival

2024 | Meissgeier | Cell Proliferation | Link

HSF1 is a prognostic determinant and therapeutic target in intrahepatic cholangiocarcinoma

2024 | Cigliano | J Exp Clin Cancer Res | Link

Cilia defects upon loss of WDR4 are linked to proteasomal hyperactivity and ubiquitin shortage

2024 | Burkhalter | Cell Death and Diseases | Link

Chromosome 8p engineering reveals increased metastatic potential targetable by patient-specific synthetic lethality in liver cancer

2024 | Huth | Science Advances | Link

BLM and BRCA1-BARD1 coordinate complementary mechanisms of joint DNA molecule resolution

2024 | Tsukada | Molecular Cell | Link

Ribosomal protein L24 mediates mammalian microRNA processing in an evolutionarily conserved manner

2024 | Tzur | Cellular and Molecular Life Sciences | Link

CSDE1 Intracellular Distribution as a Biomarker of Melanoma Prognosis

2024 | Indacochea | MDPI Cancers | Link

Evoked Weibel-Palade Body Exocytosis Modifies the Endothelial Cell Surface by Releasing a Substrate-Selective Phosphodiesterase

2024 | Na | Advance Science | Link

PPARG activation promotes the proliferation of colorectal cancer cell lines and enhances the antiproliferative effect of 5-fluorouracil

2024 | Sch | BMC Cancer | Link

Alternative Wnt-signaling axis leads to a break of oncogene-induced senescence

2024 | Kluge | Cell Death and Diseases | Link

lncRNA LINC00941 modulates MTA2/NuRD occupancy to suppress premature human epidermal differentiation

2024 | Morgenstern | Life Science Alliance | Link

NRN1 interacts with Notch to increase oncogenic STAT3 signaling in melanoma

2024 | Devitt | Cell Communication and Signaling | Link

Basis of gene-specific transcription regulation by the Integrator complex

2024 | Sabath | Molecular Cell | Link

Plakophilin 4 controls the spatio-temporal activity of RhoA at adherens junctions to promote cortical actin ring formation and tissue tension

2024 | M | Cellular and Molecular Life Sciences | Link

Dengue virus NS1 secretion is regulated via importin-subunit β1 controlling expression of the chaperone GRp78 and targeted by the clinical drug ivermectin

2023 | Denolly | mBio | Link

Prion protein conversion at two distinct cellular sites precedes fibrillisation

2023 | Ribes | Nature Communications | Link

Ethanol induces replication fork stalling and membrane stress in immortalized laryngeal cells

2023 | Hoes | iScience | Link

Identification of DUSP4/6 overexpression as a potential rheostat to NRAS-induced hepatocarcinogenesis

2023 | Klemm | BMC Cancer | Link

The function of ER-phagy receptors is regulated through phosphorylation-dependent ubiquitination pathways

2023 | Berkane | Nature Communications | Link

Fast proliferating and slowly migrating non-small cell lung cancer cells are vulnerable to decitabine and retinoic acid combinatorial treatment

2023 | Pelos | International Journal of Cancer | Link

GTPase activating protein DLC1 spatio-temporally regulates Rho signaling

2023 | Heydasch | eLife | Link

Expression of Bone Morphogenetic Protein 14 in Liver Disease and Cancer

2023 | Sommer | MDPI Livers | Link

Polarity signaling balances epithelial contractility and mechanical resistance

2023 | R | Scientific Reports | Link

Cryptosporidium uses CSpV1 to activate host type I interferon and attenuate antiparasitic defenses

2023 | Deng | Nature Communications | Link

Cold Atmospheric Plasma Triggers Apoptosis via the Unfolded Protein Response in Melanoma Cells

2023 | Zimmermann | MDPI Cancers | Link

MIA/CD-RAP Regulates MMP13 and Is a Potential New Disease-Modifying Target for Osteoarthritis Therapy

2023 | Staebler | MDPI Cells | Link

Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism

2022 | D | Nucleic Acids Research | Link

The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors

2022 | Bartl | Nature Communications | Link

The Interplay of NEAT1 and miR-339-5p Influences on Mesangial Gene Expression and Function in Various Diabetic-Associated Injury Models

2022 | Reichelt-wurm | MDPI non-coding RNA | Link

Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis

2022 | Mestre-farr | Nucleic Acids Research | Link

Optogenetic actuator

2022 | Dessauges | Molecular systems biology | Link

Knockdown of the stem cell marker Musashi-1 inhibits endometrial cancer growth and sensitizes cells to radiation

2022 | Falke | Stem Cell Research & Therapy | Link

DUSP4 protects BRAF- and NRAS-mutant melanoma from oncogene overdose through modulation of MITF

2022 | Gutierrez-prat | Life Science Alliance | Link

A JAM-A

2022 | Kummer | Journal of Cell Biology | Link

Transcriptomic landscapes of SARS-CoV-2-infected and bystander lung cells reveal a selective upregulation of NF-κB-dependent coding and non-coding proviral transcripts

2022 | Szachnowski | bioRxiv | Link

Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation

2022 | Hauffe | Cell Death Discovery | Link

Noncanonical Function of AGO2 Augments T-cell Receptor Signaling in T-cell Prolymphocytic Leukemia

2022 | Braun | AACR Journals | Link

Angpt2/Tie2autostimulatory loopcontrols tumorigenesis

2022 | Karabid | EMBO Molecular Medicine | Link

2022 | Li | Research Square | Link

JAM-A interacts with α3β1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cells

2022 | Th | Cellular and Molecular Life Sciences | Link

Ago-RIP Sequencing Identifies New MicroRNA-449a-5p Target Genes Increasing Sorafenib Efficacy in Hepatocellular Carcinoma

2022 | Reinkens | Journal of Cancer | Link

Probing protein ubiquitination in live cells

2022 | Qin | bioRxiv | Link

USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction

2022 | Hertel | Cell Reports | Link

High-throughput morphometric and transcriptomicprofiling uncovers composition of naıve andsensory-deprived cortical cholinergicVIP/CHAT neurons

2022 | Yayon | EMBO | Link

Screening of the siGPCR library in combination with cisplatin against lung cancers

2022 | Kim | Scientific Reports | Link

SNAP23-Mediated Perturbation of Cholesterol-Enriched Membrane Microdomain Promotes Extracellular Vesicle Production in Src-Activated Cancer Cells

2022 | Mitani | Biological and Pharmaceutical Bulletin | Link

Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors

2022 | Bl | Cell Death and Diseases | Link

The lysosomal proteome of senescent cells contributes to the senescence secretome

2022 | Rovira | Aging Cell | Link

Targeting the Retinoblastoma/E2F repressive complex by CDK4/6 inhibitors amplifies oncolytic potency of an oncolytic adenovirus

2022 | Koch | Nature Communications | Link

Global and precise identification of functionalmiRNA targets in mESCs by integrative analysis

2022 | Schaefer | EMBO reports | Link

YB-1 Oncoprotein Controls PI3K/Akt Pathway by Reducing Pten Protein Level

2021 | Delicato | MDPI genes | Link

Hepsin regulates TGFbsignaling via fibronectinproteolysis

2021 | Belitskin | EMBO reports | Link

AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation

2021 | Ghodke | Cell Press | Link

Identification of novel targets of miR-622 in hepatocellular carcinoma reveals common regulation of cooperating genes and outlines the oncogenic role of zinc finger CCHC-type containing 11

2021 | Gaza | Neoplasia | Link

Cold-inducible RNA binding protein promotes breast cancer cell malignancy by regulating Cystatin C levels

2021 | Ibdacochea | RNA | Link

Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation

2020 | Mercier | Nature cell biology | Link

Prevention of dsRNA-induced interferon signalingby AGO1x is linked to breast cancer cellproliferation

2020 | Ghosh | EMBO | Link

The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer

2020 | Gandhi | Nature Communications | Link

MICOS assembly controls mitochondrial innermembrane remodeling and crista junctionredistribution to mediate cristae formation

2020 | Stephan | EMBO | Link

HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth

2020 | Liebig | MDPI Cancers | Link

The UPR sensor IRE1a and the adenovirus E3-19K glycoprotein sustain persistent and lytic infections

2020 | Prasad | Nature Communications | Link

Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma

2020 | Marchetto | Nature Communications | Link

ALIX- and ESCRT-III

2020 | Larios | Journal of Cell Biology | Link

Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro

2019 | Mahli | MDPI Cells | Link

Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy

2019 | Renner | Cell Reports | Link

MRTF-A controls myofbroblastic diferentiation of human multipotent stromal cells and their tumour-supporting function in xenograft models

2019 | Werner | Nature Scientific reports | Link

C-Jun drives melanoma progression in PTEN wild type melanoma cells

2019 | Kappelmann-fenzl | Cell Death and Diseases | Link

NEAT1 is overexpressed in Parkinson

2019 | Simchovitz | The FASEB Journal | Link

The Delta Subunit of Rod-Specific Photoreceptor cGMP Phosphodiesterase (PDE6D) Contributes to Hepatocellular Carcinoma Progression

2019 | Dietrich | MDPI Cancers | Link

Role of MIA (melanoma inhibitory activity) in melanocyte senescence

2019 | Feuerer | Pigment Cell & Melanoma | Link

Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo Using Layer-by-Layer Nanoparticles

2019 | Choi | Advanced Funtional Materials | Link

53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage

2019 | Spies | Nature cell biology | Link

Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Is a Novel Prognostic Marker and Contributes to Sorafenib Resistance in Hepatocellular Carcinoma

2019 | Dietrich | Neoplasia | Link

Inhibition of peptidyl-prolyl isomerase (PIN1) and BRAF signaling to target melanoma

2018 | Braun | American Journal of Translational Research | Link

The long non-coding RNA LINC00941andSPRR5are novel regulators of humanepidermal homeostasis

2018 | Ziegler | EMBO reports | Link

SAMMSON fosters cancer cell fitness by concertedly enhancing mitochondrial and cytosolic translation

2018 | Vendramin | Nature Structural and Molecular Biology | Link

Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

2018 | Coscia | Cell | Link

FKBP51 modulates steroid sensitivity and NFκBsignalling: A novel anti-inflammatory drug target

2018 | K | European Journal of Immunology | Link

Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1

2018 | Weber | Nature Communications | Link

Transition of responsive mechanosensitive elements from focal adhesions to adherens junctions on epithelial differentiation

2018 | Noethel | MBoC | Link

Nrf2 protects stellate cells from Smad-dependent cell activation

2018 | Prestigiacomo | PLOS ONE | Link

Novel short isoforms of adenylyl cyclase as negative regulators of cAMP production

2018 | Vallin | BBA Molecular Cell Research | Link

14-3-3 proteins regulate desmosomal adhesion via plakophilins

2018 | Rietscher | The Company of Biologist | Link

Genome-Scale Signatures of Gene Interaction from Compound Screens Predict Clinical Efficacy of Targeted Cancer Therapies

2018 | Jiang | Cell Systems | Link

Cervical cancer is addicted to SIRT1 disarming the AIM2 antiviral defense

2018 | So | Oncogene | Link

The Long Noncoding RNA Cancer Susceptibility 9 and RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein L Form a Complex and Coregulate Genes Linked to AKT Signaling

2018 | Klingenberg | Hepatology | Link

The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation

2018 | Polycarpu-schwarz | Oncogene | Link

CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival

2018 | Zeiner | Acta Neuropathologica Communications | Link

Lithium chloride effectively kills the honey bee parasite Varroa destructor by a systemic mode of action

2018 | Ziegelmann | Scientific Reports | Link

Challenges of CRISPR/Cas9 applications for long non-coding RNA genes

2017 | Goyal | Nucleic Acids Research | Link

BMP6-induced modulation of the tumor micro-milieu

2017 | Stieglitz | Oncogene | Link

Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibition

2017 | Dietrich | Oncogene | Link

Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux

2017 | Ilina | Oncotarget | Link

A cautionary tale of sense-antisense gene pairs: independent regulation despite inverse correlation of expression

2017 | Goyal | Nucleic Acids Research | Link

ERAP1 overexpression in HPV-induced malignancies: A possible novel immuneevasion mechanism

2017 | Steinbach | Oncoimmunology | Link

Enhanced Stem Cell Differentiation and Immunopurification of Genome Engineered Human Retinal Ganglion Cells

2017 | Sluch | Stem Cell Research & Therapy | Link

Carboxypeptidase E transmits its anti-migratory function in glioma cells via transcriptional regulation of cell architecture and motility regulating factors

2017 | Armento | International Journal of Cancer | Link

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells

2017 | N | Scientific Reports | Link

A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis

2017 | Treiber | Molecular Cell | Link

Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper KinaseDependent Injury Signaling in Neurons

2017 | Welsbie | Neuron | Link

The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance

2017 | Seiler | Nucleic Acids Research | Link

Host AMPK Is a Modulator of Plasmodium Liver Infection

2016 | Ruivo | Cell Reports | Link

Induction of exportin-5 expression during melanoma development supports the cellular behavior of human malignant melanoma cells

2016 | Ott | Oncotarget | Link

Slug Is Increased in Vascular Remodeling and Induces a Smooth Muscle Cell Proliferative Phenotype

2016 | Coll-bonfill | PLOS ONE | Link

p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity

2016 | Adriaens | Nature Medicine | Link

SOX5 is involved in balanced MITF regulation in human melanoma cells

2016 | Korda | BMC Medical Genomics | Link

Biochemical isolation of Argonaute protein complexes by Ago-APP Judith Hauptmanna , Daniel Sch

2015 | Hauptmann | PNAS | Link

The stellate vascular smooth muscle cell phenotype is induced by IL-1β via the secretion of PGE2 and subsequent cAMP-dependent protein kinase A activation

2015 | Blirando | BBA Molecular Cell Research | Link

JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis

2015 | Tuncay | Nature Communications | Link

Importin- facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels

2015 | Schraivogel | Nucleic Acids Research | Link

Reconstitution of CPSF active in polyadenylation: recognition of the polyadenylation signal by WDR33

2014 | Sch | Genes Dev | Link

Chemical Induction of Unfolded Protein Response Enhances Cancer Cell Killing through Lytic Virus Infection

2014 | Prasad | Journal of Virology | Link

Advances in RNAi Tools and Technologies

2013 | Smith-vikos | Omics | Link