Awards and Grants

Below is the growing list of prestigious awards and grants received by siTOOLs Biotech:

Grants

		Program: Granting Organization: Grant Date: Program partner(s):	Cluster for Nucleic Acid Therapeutics Munich (C-NATM) NEW Federal Ministry of Education and Research of Germany (BMBF) July 2022 Technical University of Munich (TUM) and Ludwig-Maximilians-Universität München (LMU)
		Program info: The Cluster for Nucleic Acid Therapeutics Munich (C-NATM) is an innovation network for the development of RNA-based drugs. It is made up of research institutions such as siTOOLs Biotech, pharmaceutical companies, and private enterprise in the Munich region. It will receive five million euros in funding annually from the German government, the Free State of Bavaria, and in part from participating companies. More info


		Program: Granting Organization: Grant Date:	Next generation advanced RNA inhibition therapy to treat cardiometabolic disease - LiverTarget NEW HORIZON-AG - HORIZON Action Grant Budget-Based (EU Commission) May 2022
		Program info: LiverTarget aims at exploiting siTOOLs Biotech’s and other partners’ years of research in the field of cardiometabolic research, the identification of ceramide pathways and inflammatory targets, and the development of novel siRNA technologies and lipid formulations, to: Generate innovative siRNA pools and synthetic mRNAs to regulate ceramide and inflammatory targets in the liver. Formulate them in established human-approved liver-targeting lipid nanoparticles (LNP). Determine their efficacy in vivo in preclinical mouse models of obesity, diabetes, non-alcoholic fatty liver disease (NAFLD) and atherosclerosis. Complete the necessary safety and toxicology evaluation of the most promising lead candidates and prepare the preclinical evaluation dossier for the European Medicines Agency (EMA). More info


		Program: Granting Organization: Grant Date:	Development of an application method for a systemic varroa treatment with lithium chloride in honey bee colonies - subproject B (EAsyLife) NEW Federal Ministry of Food and Agriculture of Germany (BMEL) Feb 2021
		Program info: Honey bees are indispensable pollinator for the ecosystem as well as for agricultural production. For both, honeybees and beekeeper the worldwide distributed parasitic mite Varroa destructor represents the greatest threat. Varroosis has been proven to be the main driver for periodic colony losses and economic damage. Currently, there is no satisfactory treatment available that meets all requirements of the beekeeper. With the discovery of lithium chloride (LiCl) we present a new active substance with a high varroacidal potential combining a high efficacy against varroa mites with good tolerability for bees. Due to the systemic mode of action LiCl can be easily applied. The main objective of the project is to develop a practicable application for this new compound in order to reduce colony losses and economic losses of the beekeeper. More info


		Program: Granting Organization: Grant Date: Program partner(s):	RNAi and CRISPR: Leistungsvergleich und Anwendungsleitfaden Bayerische Forschungsstiftung (Bavarian Research Foundation) Dec 2017 Prof. Dr. Heinrich Leonhardt, Ludwig-Maximilians-Universität München
		Program info: This two year research program aims to benchmark gene disruption approaches - RNAi and CRISPR. Up to 100 genes will be disrupted with siPOOLs, single siRNAs or CRISPR sgRNAs with the aim to study the efficacy and specificity of gene disruption, robustness of phenotypes produced and costs/efforts involved. A range of techniques will be used including imaging, deep sequencing and cellular assays. More info


		Program: Granting Organization: Grant Date: Program partner(s):	BeePax - effektive Varroakontrolle mit LiCl Bayerische Forschungsstiftung (Bavarian Research Foundation) Apr 2016 Bayerische Landesanstalt für Weinbau und Gartenbau, Fachzentrum Bienen Universität Hohenheim, Landesanstalt für Bienenkunde Universität Regensburg, Lehrstuhl für Biochemie
		Program info: Following our findings (Ziegelmann et al., Scientific Reports, 2018) that Lithium can selectively kill Varroa mites without harming bees, this grant was awarded to siTOOLs Biotech and its partners to establish the appropriate and safe use of Lithium in honey bee colonies. More info.


		Program: Granting Organization: Grant Date: Program partner(s):	Athero-Flux - European Community's FP7 European Union Mar 2015 11 partners from 9 EU countries
		Program info: The Atheroflux is an EU consortium of researchers and SMEs with a know-how in lipid metabolism and RNAi that aims to identify new targets for the treatment of cardiovascular disease. This is done by focussing on a class of lipids (sphingolipids) that is highly associated with CV risk. More info


		Program: Granting Organization: Grant Date: Program partner(s):	RNA-TRAIN, a Marie Curie Initial Training Network - FP7-PEOPLE-2013-ITN European Union Sep 2014 10 partners from 8 EU countries
		Program info: RNA-TRAIN is an EU consortium consisting of 9 research labs and 2 companies seeking to uncover novel information on non-coding RNAs in the context of development, differentiation and disease. Funded by the Marie Curie initiatives of the European Commission, the program lasts for 4 years. More info


		Program: Granting Organization: Grant Date: Program partner(s):	EXIST – Existenzgründung aus der Wissenschaft Bundesministerium für Wirtschaft und Energie (BMWi) Nov 2012 University of Regensburg
		Program info: The EXIST business Start-up grant was awarded to siTOOLs Biotech and its partners based on the innovative development of siPOOLs – high complexity siRNA pools for reliable gene silencing. EXIST is a support program by the German Federal Ministry for Economic Affairs and Energy aimed at promoting entrepreneurial environment at universities and increasing numbers of successful start-ups in Germany.

Awards

		Awards: Granting Organization: Award Date:	2nd prize in Bavaria Business Plan Contest 3rd Prize at the Hochschul Gründerpreis 2014 (held in parallel) BayStartUp Jul 2014
		Program info: Organized by the innovation and entrepreneurship initiative "Netzwerk Nordbayern" in cooperation with Siemens AG, the 2nd prize for the Nordbayern (North Bavaria) Business Plan contest held on 23 July 2014 was awarded to siTOOLs Biotech. The prize consisted of 7500 EUR in winnings. siTOOLs also won the 3rd prize in a preceding competition for the Hochschul Gründerpreis (University Founder Award). More info

Grants

Awards

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