siTOOLs Biotech, co-founded by Dr. Michael Hannus and Prof. Gunter Meister in September 2013, is a spin-out of Intana Bioscience in Munich and the University of Regensburg, Germany.
Initially from Cenix Bioscience, one of the first RNA interference (RNAi) service companies, Michael gained many years of hands-on experience in RNAi screening and validation from its earliest days. Seeing off-target effects dominate results with conventional RNAi reagents, Michael decided to test the concept of complex but defined siRNA pools (siPOOLs) to "dilute" off- target effects and increase knock down specificity.
Supported by Intana Bioscience and the German EXIST program, Michael joined forces with Gunter Meister, a pioneer in RNAi biochemistry, to develop siPOOLs from proof-of-concept to a commercial product that entered the market beginning of 2014.
Since then, siTOOLs Biotech has provided reagents to
a growing number of researchers from both academia and industry within Europe, US and Asia. Working from Munich Martinsried's dynamic biotech cluster, siTOOLs Biotech applies its proprietary technology with the aim of having RNAi to live up to its full potential and early promises – as an extremely versatile, fast and cost-effective method to study gene funtion in a broad range of experimental setups.
In Dec 2015, siTOOLs Biotech launched another product, raPOOLs, that provides specific and robust enrichment of RNA for interaction analysis. Following a similar pooling approach but towards pulldown applications, raPOOLs provide robust RNA enrichment at affordable costs.
siTOOLs Biotech continues to strive towards equipping the modern day scientist with tools for easy, specific and robust analysis of gene function.
Contact us to get the most out of your gene function studies.