Advantages of Our Technology
01 Simple and fast to use
siPOOLs are compatible with a wide-range of transfection reagents and results are seen within days.
02 Highly specific and efficient
siPOOLs reduce off-targeting by 5-25 fold and achieve ‚Č• 70% gene knock-down at 1-3 nM in standard cell lines.
03 Consistent phenotypes
Phenotypes produced by sequence-independent siPOOLs are highly correlated as opposed to siRNAs.
04 Validation-inclusive Guarantee
siPOOL validation by rtqPCR is performed with possibility of re-design if less than 70% knock-down is seen under optimal transfection.
05 Customized design using latest annotations
Detailed design ensures optimized thermodynamics and paralog avoidance. Sequence info available.
06 PAGE-purified and non-toxic
All siPOOLs are PAGE-purified reducing risk of contaminants and side-effects.