riboPOOL

Efficient, Affordable Ribosomal RNA Depletion for Any Species

Detection of scientifically relevant RNAs by Next-Generation RNA Sequencing (RNA-Seq) is greatly limited by highly abundant ribosomal RNAs (rRNAs) which occupy > 90% RNA-Seq reads. Current rRNA depletion solutions however are often costly and limited to well-studied species.

Ribosomal RNA depletion pools (riboPOOLs) by siTOOLs Biotech is the market's most flexible solution in rRNA depletion. With a diverse selection of Ready-Made riboPOOLs and the ability to create your own Custom riboPOOL, riboPOOLs are ideal for sequencing experts with custom demands and scientists working on rare species.

Composed of high complexity pools of optimally-designed biotinylated DNA probes, riboPOOLs are highly efficient, even outperforming Ribo-Zero (Illumina), depleting ~10% more rRNA while leaving other RNA intact.

For microbiologists, the new Pan-Prokaryote riboPOOL provides universal rRNA depletion for a wide spectrum of microbes and is suited for metagenomic or microbiome samples. Combination riboPOOLs are also available to deplete rRNAs from samples containing multiple species.

Product Information

riboPOOLs are HPLC-purified and shipped freeze-dried at room temperature.

Ready-made riboPOOLs are available for diverse species. See full species list +

For new species, a Custom riboPOOL can be made with a one-time custom riboPOOL setup service.

For increased flexibility, riboPOOLs may be combined in custom ratios to form a Combination riboPOOL that can be used for samples containing or across multiple species. See riboPOOL Application Note under Downloads for performance data.

riboPOOLs can be obtained by Quick Order, Quote Request or through your local distributor.

Available riboPOOL formats:

Advantages of Our Technology

HOW IT WORKS

rRNA Depletion workflow