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| Official Symbol: | AMACR |
| NCBI Gene ID: | 23600 |
| Content / Scale: |
AMACRD CBAS4 P504S RACE RM |
| Official Full Name: | alpha-methylacyl-CoA racemase |
| Species: | human |
| Summary: | This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]. |
Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene AMACR.
siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.
Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.
As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.
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siPOOL- 2
2 nmol siPOOL Price: € 295,00 |
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2 nmol siPOOL Pool of pre-selected ~30 siRNAs against the target gene. HPLC-purified, in 50µM solution. 
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siPOOL- 5
5 nmol siPOOL Price: € 548,00 |
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5 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution.
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siPOOL- 5 Kit
5 nmol siPOOL 5 nmol negative control siPOOL Price: € 699,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 5 nmol / siPOOL. HPLC-purified, in 50µM solution.
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siPOOL-10
10 nmol siPOOL Price: € 692,00 |
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10 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution.
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siPOOL-10 Kit
10 nmol siPOOL 10 nmol negative control siPOOL Price: € 925,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 10 nmol / siPOOL. HPLC-purified, in 50µM solution.
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siPOOL-20
20 nmol siPOOL Price: € 1.041,00 |
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20 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution.
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siPOOL-20 kit
20 nmol siPOOL 20 nmol negative control siPOOL Price: € 1.369,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 20 nmol / siPOOL. HPLC-purified, in 50µM solution.
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siPOOL-40
40 nmol siPOOL Price: € 1.665,00 |
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40 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution.
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siPOOL-40 kit
40 nmol siPOOL 40 nmol negative control siPOOL Price: € 2.565,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 40 nmol / siPOOL. HPLC-purified, in 50µM solution.
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