Quick Order of siPOOL for PDGFRB

Not your Target Gene? Search again

Please verify & confirm your selected Target Gene:

Official Symbol:	PDGFRB
NCBI Gene ID:	5159
Content / Scale:	CD140B IBGC4 IMF1 JTK12 KOGS PDGFR PDGFR-1 PDGFR1 PENTT
Official Full Name:	platelet derived growth factor receptor beta
Species:	human
Summary:	The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017].

 

Buy a siPOOL (siRNA Pool) for PDGFRB

Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene PDGFRB.

Product Description:

siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.

Why 30 siRNAs?

Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.

Product Formats:

• Individual siPOOLs: a pool of 30 distinct siRNAs provided as a single reagent
• siPOOL kits: include an individual siPOOL and a standard negative control

As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.

Click "Login to add to Cart" to add multiple items to your shopping cart by logging into your siTOOLs Biotech account or by creating a new one.

For faster shopping, click "Order now as a Guest" to send us your Order now, then create an Account later.