Quick Order of raPOOL for PLOD2

Not your Target Gener? Search again

Please verify & confirm your selected Target Gene:

Official Symbol:	PLOD2
NCBI Gene ID:	5352
Aliases:	BRKS2 LH2 TLH
Official Full Name:	procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
Species:	human
Summary:	The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

 

Buy raPOOLs for PLOD2

There is no existing raPOOL for your gene, hence a custom raPOOL set up service is required. Please add this to cart and proceed to choose the raPOOL scale required where 2, 5 or 10 nmol is sufficient for 20, 50 or 100 reactions with the recommended use of 100 pmol raPOOL per reaction.