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Official Symbol: | PCDH15 |
NCBI Gene ID: | 65217 |
Content / Scale: |
CDHR15 DFNB23 USH1F |
Official Full Name: | protocadherin related 15 |
Species: | human |
Summary: | This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur. [provided by RefSeq, Dec 2008]. |
Order a complex pool of 30 siRNAs (siPOOL) for the specific gene knockdown of human gene PCDH15.
siPOOLs (siRNA pools) are high complexity pools of 30 optimally selected siRNAs designed to specifically knock-down the target gene of your choice.
Using 30 siRNAs at a picomolar concentration dilutes and significantly minimizes the off-target effects of each siRNA, therefore highly increasing the on-target specificity. On the other hand, individual siRNAs or low complexity siRNA pools containing only 2-4 siRNAs often display dominant off-target profiles and exhibit variable target gene knock-downs.
As reaction numbers depend on transfection efficiencies and well/plate format used, please refer to our FAQ section or siPOOL transfection protocol for more information.
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siPOOL- 2
2 nmol siPOOL Price: € 295,00 |
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2 nmol siPOOL Pool of pre-selected ~30 siRNAs against the target gene. HPLC-purified, in 50µM solution. |
siPOOL- 5
5 nmol siPOOL Price: € 548,00 |
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5 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution. |
siPOOL- 5 Kit
5 nmol siPOOL 5 nmol negative control siPOOL Price: € 699,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 5 nmol / siPOOL. HPLC-purified, in 50µM solution. |
siPOOL-10
10 nmol siPOOL Price: € 692,00 |
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10 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution. |
siPOOL-10 Kit
10 nmol siPOOL 10 nmol negative control siPOOL Price: € 925,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 10 nmol / siPOOL. HPLC-purified, in 50µM solution. |
siPOOL-20
20 nmol siPOOL Price: € 1.041,00 |
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20 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution. |
siPOOL-20 kit
20 nmol siPOOL 20 nmol negative control siPOOL Price: € 1.369,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 20 nmol / siPOOL. HPLC-purified, in 50µM solution. |
siPOOL-40
40 nmol siPOOL Price: € 1.665,00 |
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40 nmol siPOOL, pool of 30 pre-selected siRNAs against the target gene. HPLC-purified, in 50µM solution. |
siPOOL-40 kit
40 nmol siPOOL 40 nmol negative control siPOOL Price: € 2.565,00 |
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This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 40 nmol / siPOOL. HPLC-purified, in 50µM solution. |